Pyridoxal phosphate Aromatics; Vitamins and derivatives CAS:54-47-7 PYRIDOXAL-5-PHOSPHORIC ACID;

Description:

Pyridoxal Phosphate also known as PLP, pyridoxal 5'-phosphate or P5P, is the active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and deamination reactions; it is necessary for the synthesis of amino acids and amino acid metabolites, and for the synthesis and/or catabolism of certain neurotransmitters, including the conversion of glutamate into gamma-aminobutyric acid (GABA) and levodopa into dopamine. PLP can be used as a dietary supplement in cases of vitamin B6 deficiency. Reduced levels of PLP in the brain can cause neurological dysfunction.

Chemical Formula:

Basic Parameters:

MW	247.14
Stability	Hygroscopic
Melting point	140-143 °C
Storage temp	Inert atmosphere,Store in freezer, under -20°C
Synonym	3-hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinecarboxaldehyd

Raw materials:

Manganese dioxide-->Phosphorus pentoxide-->SULPHOSUCCINIC ACID ESTER-->Pyridoxine-->Pyridoxamine dihydrochloride-->3-Pyridinemethanol, 4-[[(4-ethoxyphenyl)imino]methyl]-5-hydroxy-6-methyl-, α-(dihydrogen phosphate) (9CI)-->PYRIDOXAMINE-5'-PHOSPHATE-->5-hydroxy-4-(hydroxymethyl)-6-methyl-3-pyridylmethyl dihydrogen phosphate-->Pyridoxal hydrochloride-->2-Aminoisobutyric Acid-->Pyridoxine hydrochloride-->DL-Alanine

Biological Functions:

Pyridoxal phosphate is the coenzyme form of vitamin B6. In the catalytic reaction, the intramolecular aldehyde group of pyridoxal phosphate is combined with the amino group of α-amino acid to form an aldimine, also known as Schiffbase, and then the amino acid undergoes transamination, decarboxylation or racemization according to the characteristics of different enzymes and proteins. . As a coenzyme of amino acid transaminase, decarboxylase and racemase, it plays a very important role in amino acid metabolism.